Modelling > Pathologies and modelling modes > Pathologies and parametrical modes > Arterial hypertension

The most widespread form of arterial hypertension is an essential hypertension. The main manifestation of this pathologic process is the increase of arterial pressure, that arises before the change of internal organs and systems. The increase of arterial pressure in its turn is a result of dysfunction of central nerve apparatuses, which regulate the level of arterial pressure.

It is determined, that the main factor of the arise of hypertension is the increase of total peripheral resistance. The peripheral resistance in our model is a value, inverse to the value of capillary conductivity Y_ALVL in formulas (43) and (44) describing blood flow through capillaries. The increase of total peripheral resistance is modelled by decrease of capillary systemic base conductivity Y_ALVL0 and increase of capillary systemic sympathetic sensitivity A₃.

The secondary factor of the arise of arterial hypertension is the increase of vascular wall elasticity. It is modelled by increase of arterial systemic base elasticity.

Modelling > Pathologies and modelling modes > Pathologies and parametrical modes > Arterial hypertension