Mathematical model > Neurohumoral control model > Model of cardiac center

We assume the hypothesis of cardiac center as a control system, that forms (with the help of receptor signals) the output value of neurohumoral factor, as a basis of our mathematical model of neurohumoral factor forming. Our model of cardiac center is based on a principle of a formal neuron with analog digital output.

The formal neuron of cardiac center

In our model the total activity of cardiac center is a weighted sum of receptor activity functions sending their signals to the cardiac center

(50)

The neuron transfer function is given by sigmoid

The neuron transfer function

The neurohumoral factor is the output signal of the formal neuron. So, for the neurohumoral factor a differential equation takes place:

(51)

A concrete form of the function (50) depends on a model release and can vary with its version. In the current version we have this formula:

(52)

MATLAB.SIMULINK.Formal neuron circuit